Basic Info.
Product Name
Quetiapine Fumarate
Boiling Point
395.89°c (Rough Estimate)
Density
1.0382 (Rough Estimate)
Solubility
Ethanol: Soluble10mg/Ml, Clear, Colorless to Faint
Pka
15.00±0.70(Predicted)
Delivery
2 to 5 Working Days
Transport Package
100g/Bag, 1kg/Bag, 25kgs/Drum
Specification
white powder
Product Description
Product DescriptionProduct Name | Quetiapine fumarate | CAS | 111974-72-2 | Appearance | white powder | Molecular formula | C46H54N6O8S2 | Molecular Weight | 883.09 | Assay | 99%+ | Shelf Life | 24 months when properly stored | Storage | Keep in a cool, dry, dark location |
Description: Quetiapine fumarate is an antipsychotic drug, which was successfully developed by AstraZeneca in the United States. It interacts with a variety of neurotransmitter receptors. In the brain, it has a high degree of serotonin (5-HT2) receptors. The affinity is greater than the affinity for dopamine D1 and dopamine D2 receptors in the brain. Quetiapine also has high affinity for histamine H1 receptors and adrenergic α1 receptors, and has low affinity for adrenergic α2 receptors, but has basic affinity for cholinergic muscarinic receptors receptors. There is no affinity. The activity of antipsychotic drugs, such as the conditional avoidance reflex, was positive. Clinically, it is mainly used for the treatment of adult major depression, acute manic episodes of bipolar disorder and various types of schizophrenia. It is not only effective for positive symptoms of schizophrenia, but also for negative symptoms. It can also alleviate the affective symptoms associated with schizophrenia such as depression, anxiety and cognitive deficit symptoms. Function: Quetiapine was absorbed well and metabolized completely after oral administration. The main metabolites in human plasma have no obvious pharmacological activity. Feeding had no significant effect on the bioavailability of quetiapine. The elimination half-life of quetiapine is about 7 hours. 83% of quetiapine binds to plasma proteins. Clinical trials confirm that quetiapine is effective when given twice a day. Positron emission tomography (PET) data further confirmed that the drug's occupation of 5HT2 and D2 receptors lasted 12 hours after administration.Application&Function |
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Detailed Photos
Introduction:Our Company:Wuhan Yiruo Pharmaceutical Technology Co., Ltd. was founded in 2019 and We are comprehensive enterprise with business range covering R&D, production and sales of APIs, pharmaceutical intermediates, plant extracts, all kinds of organic intermediates and so on. We bought 14,000 square meters production base in Panhu Industrial Park, established several pharmaceutical synthesis production lines, and continually expands our production capacity.
We have a professional research team of highly qualified and experienced chemists. most of our R&D team are Master and higher. With their effort, we quickly transfer the science fruit into production. Our manufacturing site is located in Wuhan which is equipped with 100L~5000L reactors; we can offer one-stop services from R&D to commercial production. (Normal reaction/ High-pressure reaction/ Catalytic reaction/ Low-Temperature reaction).Our Guarantee on quality 1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.3) Producing
a)Each operator must do self-inspection of producs and make the corresponding inspection records.b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.4.We provide the professional test data and product information ,eg: COA, HPLC/GC,MS Superiority1.Professional synthesis laboratory and manufacture /production base. 2.Strong synthesis team and service team. Professional data management.3.We provide the professional test data and product information ,eg: MSDS,COA 4..Any inquiries will be replied within 48 hours.5.All kinds of shipping methods, eg: FedEx,DHL,TNT,BY SEA and BY AIR.7.Shipping information includes Commercial Invoice,Packing List,COA,BSE/TSE.If your markets have any special requirements, please let us know.8.We can accept various payment methods,L/C,T/T,Western Union etc.9.Professional packaging can be according the customers' requirement. 10.Product application: Medicinal Chemistry , Biomedicine, Pharmaceutical intermediate, Chemistry experiment ,Biological experiments ,Chemical reagent , for R&D use.
Address:
Rm.2114, Block A, Jing Kai Wei Lai Cheng, Economic & Technological Dev. Zone, Wuhan, China
Business Type:
Manufacturer/Factory
Business Range:
Chemicals, Health & Medicine, Security & Protection
Management System Certification:
ISO 9001, ISO 9000
Company Introduction:
Wuhan Yiruo Pharmaceutical Technology Co., Ltd. is a global health industry suppliers of nutritional supplement, nootropics, peptides ( raw powder and vials) and other active pharmaceutical materials.
Our company has independent property rights of 1, 000 square meters of R& D centers, 350, 000 square meters of production plants, has a strong R & D team and good-trained production team. We have 50 to 2000 litres of reactors, more than 30 in total, can produce kilograms to tons of various types of organic synthesis and plant extracts related products. We have two patents, four categories trademark and other kinds of certificate.
With great joint efforts of our staffs, Wuhan Yiruo Pharmaceutical is getting more market for developing and manufacturing Medicine, New Compounds, Advanced Intermediates, as well as Custom Synthesis. We will make persistent efforts, providing excellent services to our customers, perfecting R& D condition, as well as enlarging business service range. We believe Yiruo will be one of the brightest star in near future with your kind support and our mutual efforts.